Kirkland Consulting

EU Legislative Interests

Clinical trial applications for pharmaceuticals, marketing applications for pharmaceuticals, REACH regulation for chemicals, EFSA assessment of food flavours and ingredients, cosmetics regulation, pesticides regulation, assessment of the safety of natural products (e.g. herbal remedies).

Communication Activities

Kirkland D, Aardema M J, Battersby R V, Beevers C, Burnett K, Burzlaff A, Czich A, Donner E M, Fowler P, Johnston H J, Krug H F, Pfuhler S, Stankowski Jr. L F (2022). A weight of evidence review of the genotoxicity of titanium dioxide (TiO2). Regul. Toxicol. Pharmacol. 136, 105263. Douglas G R, Beevers C, Gollapudi B, Keig-Shevlin Z, Kirkland D, O’Brien J M, van Benthem J, Yauk C L, Young R R, Marchetti F (2022). Impact of Sampling Time on the Detection of Mutations in Rapidly Proliferating Tissues Using Transgenic Rodent Gene Mutation Models: A Review. Environ. Mol. Mutagen. 63, 376-388. Beevers C, Uno Y, Meurer K, Hamada S, Hashimoto K, Kirkland D, LeBaron M J, Le Curieux F, Le Hegarat L, Martus H J, Masumura K, Ohyama W, Roberts D J, Vasquez M, Whitwell J, Witt K L (2023). In vivo genotoxicity testing strategies: Report from the 8th International Workshop on Genotoxicity Testing (IWGT). Environ. Mol. Mutagen. doi: 10.1002/em.22578. Epub ahead of print. PMID: 37942839. Martus H-J, Zeller A, Kirkland D (2023). Reflections in Mutation Research. International Workshops on Genotoxicity Testing (IWGT): Origins, achievements and ambitions. Mutat. Res. 792, 108469. Hendriks G, Adriaens E, Allemang A, Clements J, Cole G, Derr R, Engel M, Hamel A, Kidd D, Kellum S, Kiyota T, Myhre A, Naëssens V, Pfuhler S, Roy M, Settivari R, Schuler M, Zeller A, van Benthem J, Vanparys P, Kirkland D (2024). Interlaboratory validation of the ToxTracker assay: An in vitro reporter assay for mechanistic genotoxicity assessment. Environ. Mol. Mutagen. online version ahead of print https://doi.org/10.1002/em.22592 Kirkland D, Burzlaff A, Czich A, Doak S H, Fowler P, Pfuhler S, Stankowski L F (2024). Updated assessment of the genotoxic potential of titanium dioxide based on reviews of in vitro comet, mode of action and cellular uptake studies, and recent publications. Regul. Toxicol. Pharmacol. 154, 105734. Luijten M, van Benthem J, Morita T, Corvi R, Escobar P A, Fujita Y, Hemmerich J, Honarvar N, Kirkland D, Koyama N, Lovell D P, Mathea M, Williams A, Dertinger S, Pfuhler S, Pennings J L A (2024). Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotoxicity Testing. Environ. Mol. Mutagen. https://doi.org/10.1002/em.22640

Interests Represented

Advances interests of their clients

Member Of

Trustee of the European Environmental Mutagenesis and Genomics Society. Emeritus Member of the US Environmental Mutagenesis and Genomics Society. Health and Environmental Sciences Institute (HESI) Genetic Toxicology Technical Committee Genetic Toxicology Association (USA) UK Environmental Mutagen Society

Organisation Members

European Environmental Mutagenesis and Genomics Society. Environmental Mutagenesis and Genomics Society (USA). UK Environmental Mutagen Society. Genetic Toxicology Association (USA) Health and Environmental Sciences Institute (HESI) Genetic Toxicology Technical Committee.